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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

SectionObjectives
Special Populations- Pediatrics and geriatrics
  • 1. Age-specific pharmacotherapy considerations
    - Renal and hepatic impairment
    • 1. Dose adjustment strategies
      Part II: Applied Clinical Decision Making- Case-based pharmacotherapy scenarios
      • 1. Therapeutic optimization in multi-morbidity
        • 2. Complex patient management cases
          Patient Care and Pharmacotherapy Principles- Therapeutic decision making
          • 1. Drug selection and individualized therapy
            • 2. Evidence-based medicine application
              - Medication management
              • 1. Dosing optimization and adjustments
                • 2. Adverse drug reaction management
                  Disease State Management- Cardiovascular disorders
                  • 1. Hypertension and heart failure
                    • 2. Acute coronary syndromes
                      - Endocrine and metabolic disorders
                      • 1. Diabetes management
                        • 2. Thyroid and lipid disorders
                          - Infectious diseases
                          • 1. Antimicrobial therapy selection
                            • 2. Resistance management principles
                              Part I: Knowledge-Based Assessment- Foundational pharmacotherapy knowledge
                              • 1. Guideline-based treatment approaches
                                • 2. Drug mechanisms and clinical use

                                  BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

                                  1. A 51-year-old male patient reports waking up in the middle of the night and being unable to go back to sleep, but he has no problem falling asleep. The patient says he feels exhausted most days of the Week at Work. His physician prescribes zolpidem 3.5 mg sublingually as needed.
                                  What is the most appropriate counseling point about zolpidem for this patient?

                                  A) It is unlikely to cause sleep during driving.
                                  B) It may be taken for middle-of-the-night awakenings.
                                  C) It should be taken shortly before bedtime.
                                  D) It should be taken with a full glass of water.


                                  2. A 24-year-old Woman complains of dysuria, hesitancy in urination, and frequent urination for the past 2 days. She has no costovertebral tenderness, fever, or history of UTls. Urinalysis data are:
                                  * pH: 5.5
                                  * WBCS: 15 cells/ul
                                  * RBCS:5 Cells/uL
                                  * Bacteria: Numerous Gram-negative rods
                                  * Negative for protein, glucose, and WBC casts
                                  For this patient, assuming that local resistance rates are low, which of the following would be an empiric cost-effective regimen?

                                  A) Azithromycin 1 g single dose
                                  B) Amoxicillin 500 mg three times daily for 7 days
                                  C) Ciprofloxacin 500mg twice daily for 7 days
                                  D) Sulfamethoxazole/trimethoprim one double-strength tablet twice daily for 3 days


                                  3. A 54-year-old male patient (BSA = 1.8 m2) is being treated for head and neck cancer with the following regimen:
                                  * Cisplatin 100 mg/m2 intravenously on day 1
                                  * 5-Fluorouracil 1000 mg/m2 intravenously by continuous infusion on days 1 through 5
                                  * Ondansetron 16 mg intravenously
                                  Which of the following is the appropriate administration instruction for ondansetron?

                                  A) One dose 30 minutes before Cisplatin and a repeat dose immediately before 5- fluorouracil on day 1; then repeat daily before 5-fluorouracil
                                  B) Daily prior to 5-fluorouracil infusion on days 1 through 5
                                  C) Thirty minutes before Cisplatin on day 1
                                  D) Thirty minutes prior to Cisplatin, thereafter as needed for nausea


                                  4. Which of the following pharmacoeconomic analyses incorporates patient preferences regarding health?

                                  A) Cost-effectiveness
                                  B) Cost-minimization
                                  C) Cost-utility
                                  D) Cost-benefit


                                  5. Two antihypertensive regimens have been compared in 50 patients with mild hypertension.
                                  Treatment A decreased mean diastolic blood pressure to 81 mm Hg, and Treatment B decreased it to 85mm Hg (p = 0.08, a priori critical a = 0.05). The most reasonable interpretation of these results is that the difference between treatments is:

                                  A) Clinically but not statistically significant.
                                  B) Statistically and clinically significant.
                                  C) Statistically but not clinically significant.
                                  D) Neither statistically nor clinically significant.


                                  Solutions:

                                  Question # 1
                                  Answer: C
                                  Question # 2
                                  Answer: D
                                  Question # 3
                                  Answer: C
                                  Question # 4
                                  Answer: D
                                  Question # 5
                                  Answer: A

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